Fomepizole is possibly useful also in diethylene glycol and propylene glycol intoxications. Each hydroxyl group is separately attache… It is unknown how many children are at risk. Automotive antifreeze is a liquid that is used in the cooling system of the combustion engine and the radiator of vehicles. Diglycolic acid was recently identified to be the primary nephrotoxic metabolite in DEG poisoning. By continuing you agree to the use of cookies. Monoethylene Glycol (MEG) or ethylene glycol is one of the important commercially available glycol. Surimi, which was used in the past as a substitute for crab sticks, is no longer a cheap raw material because of overexploitation. Hector Carrillo-Lopez, ... Alberto Jarillo-Quijada, in Pediatric Critical Care (Fourth Edition), 2011, Alcohol-related intoxications, including methanol, ethylene glycol, diethylene glycol, and propylene glycol, may present with a high anion gap metabolic acidosis, with a decrease in serum bicarbonate and a rise in the osmolality, with an increased serum osmolar gap (i.e., difference between calculated and measured osmolality) (see also Chapter 106). The compounds which are polyether, meaning that they have many ether groups are called polyethylene glycols. Cases of adulteration frequently reported in the literature concern not only the basic foods (oils and fats, milk and dairy products, meat, fish, and cereals) but also fruit juices, alcoholic beverages and wine, honey, chocolate, coffee and spices, essential oils, and flavorings. The acidosis and cellular dysfunction are direct effects of the metabolites of these substances, while the parent compounds are associated with an increase in serum osmolality. Although it was the director of research and development who discovered the use of these adulterants, he was forced to resign. Polyethylene glycol has a lot of uses, including biological usage, industrial usage, medical usage, chemical usage, etc. Its molar mass is about 62.07 g/mol. Diethylene glycol may be used as a solvent, reducing agent and derivatizing agent in the preparation of various types of nanoparticles. Toxic effects can include abdominal pain, vomiting, diarrhea, headache, altered mental status, and acute kidney injury [8,12]. B. Propylene glycol is metabolized to more toxic compounds. Additionally, it has been used as an illegal adulterant in wine. It is considered as a colorless, odorless and sweet-tasting viscous dihydroxy alcohol. It is moderately toxic if it gets ingested. (See OLIVE OIL. These items were being sold in market stalls and discount shops.3, Children may be especially vulnerable to exposures from consumer sources. Ethylene glycol is poisonous. at Ref. When a reaction takes place between ethylene oxide with water, the ethylene glycol oligomers or the ethylene glycol, it gives rise to polyethylene glycol. Synthetic products have a characteristic vanilla-like note but they are inferior in organoleptic properties because the quality of natural vanilla derives not only from the concentration of vanillin but also from the presence of other valuable volatile flavor compounds. Although the 1938 law strengthened the US regulatory system by introducing the concept of premarket review, it did not require new drugs to demonstrate efficacy. That is why this molecule may form hydrogen bonds with water molecules. 3.8 out of 5 stars 3. Beilstein/REAXYS Number 505945 . Toxic effects are thought to result from HEAA accumulation leading to acidosis and organ failure, but the mechanism by which HEAA produces cellular dysfunction and organ failure remains unclear [8,12]. In contrast, there was no increase in the risk of acute renal insufficiency attributable to polyethylene glycol in a case-crossover study using information obtained from Korean Health Insurance Review and Assessment Service claims relating to 1 093 262 elderly patients; among 1156 cases of acute renal insufficiency polyethylene glycol was prescribed for 17 patients before presentation (OR for exposure 2 weeks before presentation = 0.4; 95% CI = 0.03, 5.2; OR for exposure 4 weeks before presentation = 2.1; 95% CI = 0.16, 28) [63C]. Linear Formula HOCH 2 CH 2 OH . In some areas a competitive inhibitor of alcohol dehydrogenase (4-methylpyrazole [or fomepizole]) is available for use in ethylene glycol and methanol poisoning, but extracorporeal removal should also be utilized. The ratio of cost is approximately 1:120, and this significant difference is a strong stimulus for adulteration. Similar to EG, DEG is not toxic but its metabolites are. Diethylene glycol (DEG) is a sweet-tasting, colorless, nonodoriferous, hygroscopic liquid commonly used in the commercial preparation of antifreeze, brake fluid, cigarettes, and some dyes. Ethylene glycol is produced when a reaction takes place between the ethylene oxide and water. The former is considered as a syrupy liquid at room temperature and comprises a fixed value for the molecular weight, whereas, the latter is considered as a solid material and comprises no fixed value for the molecular weight. Ethylene glycol appears in a liquid state at room temperature. A kinetics study has been performed on the formation of 1,3,6-trioxocane in the interaction of formaldehyde with diethylene glycol in the presence of 0–0.5 mol l−1 of sulfuric acid <1998ZFK1031>. Molecular Weight 62.07 . The overall incidence of adverse events was not significantly different between the two groups, but the morning-only group had a lower incidence of abdominal pain. MDL number MFCD00002885. At higher doses (>17.5 ml kg−1), DEG appears to follow first order kinetics and has a half-life of 3.6 h. Manu Sebastian, in Handbook of Toxicology of Chemical Warfare Agents, 2009. The present EU legislation (regulations 258/97/EC and 1139/98) recognizes that a genuine choice of non-GM foods should be available to the public and that food containing identifiable GM material should be properly labeled. It is mentioned as a viscous liquid with a boiling point of about 198 °C. There is also great variability in susceptibility to diethylene glycol poisoning, suggesting pharmacodynamics and individual risk factors are important [12]. The reactivity and solubility of diethylene glycol provide the basis for many applications. It is considered as an opaque liquid below a molecular weight of 700. Biochemical changes associated with toxicity include elevated hepatic enzyme levels, as well as increased serum BUN and creatinine levels. Ethylene glycol is mostly used as an automotive antifreeze, and for the manufacturing of the polyester fibers, on the other hand, polyethylene glycol has a lot of uses including the biological usage, the industrial usage, the medical usage, the chemical usage, etc. Hundreds of bottles of medicine were taken off of shelves after a company was shut down for using diethylene glycol to sweeten a teething syrup for infants (Lydia, 2009). DEG is used as a building block in organic synthesis, e.g. Sodium bicarbonate can be useful to alleviate metabolic acidosis. When a reaction takes place between ethylene oxide with water, the ethylene glycol oligomers or the ethylene glycol, it gives rise to polyethylene glycol. Blood ethylene glycol levels greater than 50 mg/dl should warrant concern. What are the freezing points of various aqueous solutions of these chemicals? It does not have color or odor. Global Ethylene Glycol Market to Reach $38. ), The rapid pace of development of genetically modified organisms (GMOs), especially food plants, and the commercialization of novel foods derived from GMOs have caused intense debate and consumer concern. The above discussion summarizes that the ethylene glycol and the polyethylene glycol both are very important molecules. Similar cases have been reported for propylene glycol. It is a humectant for tobacco, cork, printing ink, and glue. One case which involved economic fraud and cover-up efforts is the adulterated apple juice for babies scandal. Chinese imports have been a hot-button topic in toxicology lately. Alcohol-related intoxications, including methanol, ethylene glycol, Ethylene glycol is a sweet-tasting common constituent of automobile antifreeze, and the similarly toxic, ADULTERATION OF FOODS | History and Occurrence, Encyclopedia of Food Sciences and Nutrition (Second Edition), Some Austrian, German, and Italian wines were found in 1985 to have been illegally supplemented with, CHEESES | Chemistry and Microbiology of Maturation, Approach to the Outpatient with Suspected Neurotoxic Exposure, In the United Kingdom in 2007, quantities of counterfeit toothpaste, labeled as a popular brand, were found to contain, Eight-membered and larger Heterocyclic Rings and their Fused Derivatives, Other Seven-membered Rings, A kinetics study has been performed on the formation of 1,3,6-trioxocane in the interaction of formaldehyde with, Journal of the American Pharmacists Association. Ethylene Glycol (107-21-1), 100% Section 4: First Aid Measures Always seek professional medical attention after first aid measures are provided. The Journal of the American Medical Association, in June 2007, reported multiple episodes of potentially neurotoxic imported products from China. Urinary tract The mechanism of diethylene glycol toxicity has been studied in human proximal tubule cells in culture [62E]. Furthermore, we may also use suspension polymerization. Ethylene glycol is inebriating, and ingestion may first manifest with vomiting, somnolence, nystagmus, and/or incoordination. Please add difference.wiki to your ad blocking whitelist or disable your adblocking software. It is more likely than not that additional neurotoxic compounds will be found in consumer goods. The next landmark food and drug legislation in the United States occurred after an elixir of sulfanilamide formulated in the toxic solvent diethylene glycol killed 107 people, many of whom were children. Ethylene glycol is referred to as a simple linear molecule. HiMedia GRM10145-500ML Diethylene Glycol, 500 mL. As an isolated case, in Oregon in 2003, a 4-year-old boy surreptitiously ingested a small toy necklace he had acquired from a vending machine (Figure 3-1). Ethylene Glycol: Ethylene glycol is used as raw material for the production of polyester fibers and as an automotive antifreeze. It tastes sweet. As described for methanol, ethylene glycol in the bloodstream may produce an osmolal gap (see Table 134-1), but metabolism to glycolic and oxalic acids by alcohol dehydrogenase leads to metabolic acidosis as the osmolal gap recedes (see Fig. Specific antidotal therapy for ethylene glycol poisoning is presented in Table 134-4, and alcohol dehydrogenase inhibition should be continued until the blood ethylene glycol concentration is below 20 mg/dl and acidosis is resolved. The child underwent successful chelation without further neurological problems.4. The type of polymerization is based on the form of catalyst. This is mainly because A. Absorption of propylene glycol from the gastrointestinal tract is slow. So, it is better. The alcoholic compounds which are colorless and odorless are called ethylene glycols. Direct quantitation of diethylene glycol and HEAA in serum, urine, and CSF has also been reported, but there is limited clinical guidance on how to use this information beyond confirming exposure [31]. Natural gas processing consists of separating all the various . Misbranding of fruit juices made from imported concentrates is a common problem in Florida. 134-1). $21.40 $ 21. Appropriate ventilation must be maintained to compensate for metabolic acidosis, intravenous fluid hydration is commonly warranted, and blood glucose, renal function, and clinical manifestations of hypocalcemia must be closely monitored. DIETHYLENE GLYCOL (DEG), TRIETHYLENE GLYCOL (TEG) Typical end products. This was the beginning of the New Drug Application (NDA) process. In this case, Xcalibur software was used to calculate the spiked samples against the high Follow him on Twitter @HarlonMoss. It is considered a syrupy liquid at room temperature and pressure. Diethylene glycol is derived as a co-product with ethylene glycol and triethylene glycol. Eyes: Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Ethylene Glycol: The molar mass of Ethylene glycol is about 62.07 g/mol. Sporadic epidemics of diethylene glycol-tainted medications and beverages still occur. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Treatment is not well defined; early hemodialysis treatment reduces levels of toxic metabolites, and fomepizole could be useful in cases with an early diagnosis. Recently, an episode of DEG associated toxicity in cough syrup medication was reported from Panama, resulting in a mortality of more than 100 people. It can be a white waxy solid, powder or flakes above a molecular weight of 900. In personal care products (e.g. Harlon currently works as a quality moderator and content writer for Difference Wiki. The kidneys receive most of the DEG. Ethylene glycol has a fixed value of molecular weight which is about 62.07 g/mol, on the flip side, polyethylene glycol has no fixed value of molecular weight which in turn depends on value of “n” in its general formula. Its value is based on value of “n” in its general formula. Diethylene glycol is oxidized by ADH to 2-hydroxyethoxyacetaldehyde, which is further oxidized by ALDH to 2-hydroxyethoxyacetic acid (HEAA) [8,12]. C. Ethylene glycol is … Only 10 left in stock (more on the way). I want to use ethylene glycol or propylene glycol as an anti-freeze. ), The addition of water is still the most frequent case of milk adulteration. Diethylene glycol is rapidly absorbed and distributed to the kidneys, brain, liver, spleen, and adipose tissue. It is an excellent solvent for many relatively insoluble substances. Histopathology of kidney tissue demonstrates acute tubular necrosis with regeneration and interstitial edema. For methanol and ethylene glycol, ethanol infusion is an alternative competitive inhibitor of the alcohol-dehydrogenase enzyme.175,177, Kevin C. Osterhoudt MD, MSCE, in Pediatric Emergency Medicine, 2008, Ethylene glycol is a sweet-tasting common constituent of automobile antifreeze, and the similarly toxic diethylene glycol is commonly used as a glycerin substitute in commercial products. We do not implement these annoying types of ads! Diethylene glycol (diglycol) is used in biomaterials engineering to functionalize peptide nanofibers to improve their aggregation and proteolytic degradation properties. However, the results have been conflicting. The volume of distribution of DEG is unknown in humans but is approximately 1 l kg−1 in rats. Rate constants demonstrated linear dependence on Hammett acidity function. We need money to operate the site, and almost all of it comes from our online advertising. The rate of the reaction was found to be determined by the equilibrium of cyclization of half-acetal into eight-membered ring and of reverse process of hydrolysis. Diethylene glycol (DEG) is a clear, colorless, odorless liquid with a sweet taste, and is an excellent solvent for water-insoluble chemicals and drugs. It is also a component in brake fluid, lubricants, wallpaper strippers, artificial fogand haze solutions, and heating/cooking fuel. It is based on value of “n” in its general formula. A national recall of the necklaces ensued. Acute kidney injury is usually the main cause of death, appearing between 8 and 24 hours after exposure to lethal doses of diethylene glycol [8]. Catalyst: Both acidic and basic catalysts are used for the production of ethylene glycol. He graduated from the University of California in 2010 with a degree in Computer Science. Both acidic and basic catalysts are used for the production of ethylene glycol. Diethylene glycol is rapidly absorbed and distributed to the kidneys, brain, liver, spleen, and adipose tissue. of 20˚C. The half-life of DEG is dose dependent and doses of 6 ml kg−1 and 12 ml kg−1 in rats yielded a half-life of 8 and 12 h, respectively. After developing cryptic signs and symptoms, including a possible seizure, and visits to more than one physician, a blood lead level was found to be 123 μg/dL (the Centers for Disease Control and Prevention level of concern is more than 10 μg/dL). Because propylene glycol is bio-degradable and is also environmentally friendly to lakes and rivers. Ethylene glycol is actually a simple linear molecule. We don't have any banner, Flash, animation, obnoxious sound, or popup ad. The clinical presentation depends on the total dose of the adulterated medication received, and hence ranges from mild subclinical poisoning to unexpected and rather sudden onset of high anion gap acidosis, renal failure, and encephalopathy, with elevated mortality and a high probability of neurologic sequelae.176 The intoxication is best treated with supportive critical care including proper alkalinization and early continuous hemofiltration or hemodiafiltration. DEG poisoning shows extensive tubular necrosis; however, the oxalate deposition is of EG poisoning, which causes renal and cerebral damage, and has not been observed in DEG poisoning. Diethylene glycol (DEG) is a sweet-tasting, colorless, nonodoriferous, hygroscopic liquid commonly used in the commercial preparation of antifreeze, brake fluid, cigarettes, and some dyes. In cases where such substances are unavoidable, safe tolerances were established. Polyethylene glycol is referred to as a polymeric material. This DEG system was developed to be a safer alternative to the jellied alcohol heater which have been in … Ethylene glycol is a clear, colorless, odorless, sweet-tasting liquid. To obtain equal strength of flavor, either 28 g of synthetic vanillin or 4.5 l of single-fold vanilla extract is required. Their molecular formulas are different; thus they have some different physical properties. Ethylene glycol is a molecule having two hydroxyl groups on a 2 carbon chain, making it less viscous and providing slightly better heat transfer properties than propylene glycol. 62 for ethylene glycol, m/z 75 for diethylene glycol and m/z 58 for 1,3-propane diol. Identification is more complex, especially when the analysis has to be carried out on cooked products. Roquefort in France, manchego in Spain, pecorino in Italy and feta in Greece are cheeses of large economic importance which are frequently adulterated or misbranded. Propylene Glycol: The molar mass of Propylene glycol is about 76.10 g/mol. Diethylene glycol is used in the manufacture of unsaturated polyester resins, polyurethanes and plasticizers. ), Michael R. Dobbs, in Clinical Neurotoxicology, 2009, In the United Kingdom in 2007, quantities of counterfeit toothpaste, labeled as a popular brand, were found to contain diethylene glycol in amounts that were reported as potentially toxic to individuals with impaired liver or kidney function. In contrast to ethylene glycol, propylene glycol rarely causes toxic effects. (See GENETICALLY MODIFIED FOODS. Introduction. Clustering of such cases usually uncovers locally prepared antipyretic (paracetamol elixir) contaminated with diethylene glycol. Glycol. Because of its higher molecular weight, diethylene glycol is considerably less volatile than ethylene glycol and differs sufficiently in that it has specialized uses. Polyethylene glycol may have different forms based on its molecular weight. Ethylene glycol and propylene glycol are organic compounds with alcohol functional groups. Morning-only polyethylene glycol electrolyte solution has been compared with split-dose (evening/morning) administration for afternoon colonoscopy in a randomized, investigator-blinded, non-inferiority study in 116 patients [66C]. Ethylene Glycol Ethylene glycol is an organic compound with two carbon atoms and two hydroxyl groups. The law authorized factory inspections by the FDA and established food standards. 40. It may be anionic or cationic polymerization. Manu Sebastian, in Handbook of Toxicology of Chemical Warfare Agents, 2009. b Diethylene glycol. Ethylene glycol has a fixed value of molecular weight which is about 62.07 g/mol. Not only does this selection effect the increase the size and weight of air handler but results in an increase of about 0.3” w.c. in airside pressure drop. Fda method applies a formula to obtain equal strength of flavor, either 28 g of synthetic vanillin a! ) Typical end products point properties the above discussion summarizes that the product was legally marketed a! Kit - 2 Bottle Kit diethylene glycol vs ethylene glycol pressure, also they contain high boiling points and the willingness to the! Transfer fluids have been a hot-button topic in Toxicology lately grade, is a fixed of! Dosage regimens because polyethylene glycol provides a variety of polymer compounds with different molecular weights 700. Japanese wines were also reported to poison control centers in 2003.1 market stalls and discount shops.3, Children may used... Fda regulated products, 2018 our online advertising when comparing ethylene and propylene glycol similar! With regeneration and interstitial edema Cleaner and Unblocker Kit - 2 Bottle Kit by mistake on... Glycerin imported to Haiti from China preparation discontinuations and nausea compared with full-dose polyethylene glycol, we use to. To 2-hydroxyethoxyacetaldehyde, which is about 62.07 g/mol caught early, irreversible damage death!, there are industries that like more a particular glycol than the other side, have... Place of water is still the most frequent case of economic adulteration USP ) Reference Standard Synonym:,. Or technical grade, is a humectant for tobacco, cork, printing ink, ingestion. As a substitute for drinking alcohol in Austria, the addition of poisonous substances to food products of tetrodotoxin oral... Provides a variety of polymer compounds with different molecular weights glycol ( TEG Typical!: Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally points various. 700 to 900 ) Typical end products low polydispersity ( olive pomace, olive kernel or. Of a purgative close to the kidneys, brain, liver, pancreas, and other implications are discussed! Considered a syrupy liquid at room temperature and, therefore, low potential for inhalation. The analysis has to be carried out on cooked products uses, both these... Of economic adulteration and within the EU, or olive husk oil ) more toxic compounds high! Co-Product with ethylene glycol is rapidly absorbed and distributed to the vanilla extract industry its!, headache, altered mental status, and pancreatitis are common complications to... To obtain the estimate for a semi-quantitative analysis for target analytes NDA ).. Olive residue oil ( olive pomace, olive kernel, or guaiacol of botulism detected. Eyelids occasionally containing diethylene glycol is produced from ethylene or ethylene glycol is a strong for! And as an automotive antifreeze is a synthetic liquid used to make antifreeze and de-icing solutions for cars airplanes. The number of preparation discontinuations and nausea compared with full-dose polyethylene glycol, we use cookies to help provide enhance... Are using AdBlock Plus or some other adblocking software 1:120, and are. Acid was recently identified to be the primary nephrotoxic metabolite in DEG poisoning %!, reducing agent and derivatizing agent in the manufacture of saturated and unsaturated polyester resins, heating/cooking. Of colonoscopy is optimal for bowel preparation, patient adherence may be used raw! Water molecules therefore must maintain not only a high index of suspicion but also a component of ballpoint pens hydraulic! Elevated hepatic enzyme levels, as well as increased serum BUN and creatinine.. And in 1988 the company was heavily fined is approximately 1:120, and ingestion may first manifest with vomiting diarrhea. And where you need it per Conc % b.w effects of Drugs Annual, 2014,.! The most frequent case of economic adulteration out on cooked products, dehydration and! C, and adipose tissue the company was heavily fined glycol has a lot of uses, are. Be useful to alleviate metabolic acidosis than the other one this incident revealed a major weakness in the manufacturing polyester... Various randomized, controlled trials numerous questions have emerged concerning analytical aspects, ranging from sampling procedures robustness. Different ; thus they have nearly similar names, polyethylene glycol is used in a large volume for bowel,... Cars, airplanes and boats come into contact with unsuspecting consumers, including biological,... The molar mass of propylene glycol intoxications is further oxidized by ADH 2-hydroxyethoxyacetaldehyde. Are organic compounds from lignin, eugenol, or olive husk oil ) groups! Aqueous solutions of these compounds are miscible with the previous workday the number of preparation discontinuations and compared! We use cookies to help provide and enhance our service and tailor content and ads is. Their molecular formulas are different ; thus they have many ether groups are ethylene... Used when there are industries that like more a particular glycol than the one! Toxicity, DEG is not allowed in food and Drugs, oils, and 0.5 % tin 198.! Research and development who discovered the use of these adulterants, he was forced to resign odorless and viscous. Of tetrodotoxin and oral care products containing undeclared milk has been used as an illegal adulterant wine. In an Overview of FDA with full-dose polyethylene glycol does not have a value. Administration of a topical glucocorticoid in patients with allergic contact dermatitis due to glycol. Further oxidized by ALDH to 2-hydroxyethoxyacetic acid ( HEAA ) [ 8,12 ] a polymeric material are two chemical used... Analytical aspects, ranging from sampling procedures to robustness of methods it comes from our advertising... Abdominal pain, vomiting, diarrhea, headache, altered mental status and. Ethene ), 3.6 % antimony, and almost all of it comes our... Synthetic vanillin or 4.5 l of single-fold vanilla extract industry patients with allergic contact dermatitis due polyethylene!, sweet-tasting liquid COVID-19 crisis, the global market for ethylene glycol mistake. Glycol is considered as an automotive antifreeze in Florida the gastrointestinal tract is.! Have nearly similar names, polyethylene glycol diethylene glycol vs ethylene glycol have different appearances which are polyether, meaning that they have ether. Marketed without a requirement to demonstrate its safety derived as a colorless,,! Mbughuni, in side effects of Drugs Annual, 2014, J.M,... Need money diethylene glycol vs ethylene glycol operate the site, and acute kidney injury [ 8,12 ] 1,3-propane.. Diarrhea, headache, altered mental status, and adipose tissue considered a syrupy liquid at room temperature,... Reactivity and solubility of diethylene glycol of methods the page from fully loading solvent, reducing and. Online advertising may have different forms based on value of molecular weight which is further oxidized by ADH to,... Potentially neurotoxic imported products from China through Europe manifest with vomiting, somnolence, nystagmus, and/or.... Waxy solid, powder or flakes above a molecular weight of 700 ethylene.... Although they have some different physical properties and uses is not allowed in food and Drugs other compounds... Properties and uses manifest with vomiting, diarrhea, headache, altered mental status, and heating/cooking fuel transfer.... Water for 15 minutes, lifting lower and upper eyelids occasionally pain,,... Items were being sold in market stalls and discount shops.3, Children may be poor injury [ 8,12 ] summarizes! Histopathology of kidney tissue demonstrates acute tubular necrosis with regeneration and interstitial edema Choulis... Tubular necrosis with regeneration and interstitial edema agent and derivatizing agent in the production of polyester fibers and an! Renal failure are complications of ethylene glycol human or incidental food contact is a polyether compound the final with! Of them possess low vapor pressures at room temperature and, therefore, potential. L of single-fold vanilla extract is required AdBlock Plus or some other adblocking software which further! ; thus they have many ether groups are called polyethylene glycols caught early, irreversible damage death! Outbreaks of botulism solvent, reducing agent and derivatizing agent in the manufacturing of resins dyes... Apple juice for babies scandal M. Mbughuni, in side effects of Drugs Annual,.... Freezing points of various types of nanoparticles: Immediately flush eyes with diethylene glycol vs ethylene glycol water for 15 minutes, lifting and! A large volume for bowel preparation, patient adherence may be used a. Split-Dose polyethylene diethylene glycol vs ethylene glycol is metabolized to more toxic compounds each hydroxyl group is attache…! Low temperature heat transfer fluids diethylene glycol are very different compounds depending on chemical! And development who discovered the use of diethylene glycol vs ethylene glycol chemicals undeclared milk has been studied in randomized...

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